P-hydroxybenzaldehyde, the molecular formula is C7H6O2, molecular weight is 122.12, a pale yellow or off-white crystal with a slight aromatic odor. The main use is for the pharmaceutical industry and the perfume industry's important intermediates. At present, the industrial production mainly includes raw materials such as phenol, p-cresol and p-nitrotoluene. The process characteristics are easy to obtain raw materials, and the manufacturing process is relatively simple, but the yield is low and the cost is high.

Chinese alias: 4-hydroxybenzaldehyde

English name: p-Hydroxybenzaldehyde

English alias: 4-Hydroxybenzaldehyde

CAS No.: 123-08-0

Molecular formula: C7H6O2

Molecular weight: 122.12

Purity: ≥98.0%

Rating: CP

MDL number: MFCD00006939

Beilstein number: 471352

EC number: 204-599-1

Trait description

P-hydroxybenzaldehyde is a pale yellow or off-white crystal with a slight aromatic odor

Physical parameter

Melting point: 112-116 ° C (lit.)

Relative density 1.129 (30/4 ° C)

Boiling point: 246.6 °C

Refractive index: 1.57055 (130 ° C)

Appearance: yellow or light brown powder

Flash point: 101.3 ° C

Storage and transportation

Sealed in cool and protected from light

Security term

1. Avoid contact with skin and eyes.

2. If you accidentally come into contact with your eyes, rinse immediately with plenty of water and seek medical advice.

3. Wear appropriate protective clothing.

Risk term

1. Irritating to eyes, respiratory system and skin.

Hazard statement

Danger code: Xi

Hazard level: 36/37/38

Security level: 26-36

Solubility

Soluble in ethanol; ether; acetone; ethyl acetate, DMF; slightly soluble in water (solubility in water at 30.5 ° C 1.388 g / 100 ml), soluble in benzene (solubility in benzene at 65 ° C is 3.68 g / ml).

Use

Used as a raw material for polymers and pharmaceuticals

P-hydroxybenzaldehyde is an important intermediate in the pharmaceutical industry and the perfume industry. It is also used in the synthesis of pesticide herbicide bromoxynil and hydroxydicarbonitrile, as well as the production of fungicides, photographic emulsifiers, nickel-plated brighteners, liquid crystals, etc. It can be used in the pharmaceutical industry to synthesize amoxicillin (amoxicillin), antibacterial synergist trimethoprim (TMP), 3,4,5-trimethoxybenzaldehyde, p-hydroxyglycine, hydroxyaminobenzyl cephalosporin , artificial gastrodia, azadirachtin, escarol, etc.; used in the perfume industry for the synthesis of vanillin, ethyl vanillin, jasmonaldehyde, syringaldehyde, anisaldehyde and raspberry ketone and other spices.